Novel Method for Quantifying AhR-Ligand Binding Affinities Using Microscale Thermophoresis
The aryl hydrocarbon receptor (AhR) is a highly conserved cellular sensor of a variety of environmental pollutants and dietary-, cell- and microbiota-derived metabolites with important roles in fundamental biological processes.Deregulation of the AhR pathway is implicated in several diseases, including autoimmune diseases and cancer, rendering AhR